Set
myForm.KeyPreview = true;
Create a handler for the KeyDown event:
myForm.KeyDown += new KeyEventHandler(Form_KeyDown);
Example of handler:
// Hot keys handler
void Form_KeyDown(object sender, KeyEventArgs e)
{
if (e.Control && e.KeyCode == Keys.S) // Ctrl-S Save
{
// Do what you want here
e.SuppressKeyPress = true; // Stops bing! Also sets handled which stop event bubbling
}
}